mantispy.ds.neuropainting

mantispy.ds.neuropainting(cache_dir=None)

Astrocytes and neurons, 1,691 wells imaged at 20x and 63x.

cpg0038-tegtmeyer-neuropainting. One plate barcode appears in more than one batch, so the observations are not indexed by plate and well.

The base is pre-built by scripts/build_staged_datasets.py from the six raw plate tables and rehosted on scverse-exampledata, so the loader fetches a single h5ad rather than reassembling it on every call.

Parameters:

cache_dir (str | Path | None (default: None)) – Where to keep the download. Defaults to mantispy.settings.cache_dir.

Return type:

AnnData

Returns:

Wells by features at well resolution, with Metadata_CellCount and Metadata_SiteCount, read with mantispy.io.read().

Notes

No Metadata_Perturbation is set. This is a genotype-and-donor comparison (a control-versus-deletion contrast over patient and isogenic lines) rather than a reagent perturbation screen, and its genotype and line columns differ between plates, so the per-plate column intersect keeps none of them. Group with an explicit groupby= on the column the analysis needs.